Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26364530 | 0.86 | PREP (0.52) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL26364677 | 0.82 | PREP (0.59) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL26364694 | 0.81 | PREP (0.51) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL10756725 | 0.79 | PREP (0.62) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL489615 | 0.79 | PREP (0.62) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL10756717 | 0.79 | PREP (0.62) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL5755965 | 0.78 | PREP (0.54) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL205438 | 0.78 | PREP (0.64) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL774705 | 0.78 | PREP (0.64) | PREPCTRB1NPSR1TSHRL3MBTL1 | |
| SCHEMBL18901785 | 0.78 | PREP (0.64) | PREPCTRB1NPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |