SCHEMBL4973104

SCHEMBL4973104

COc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 16/20 1.00
MAOA P21397 11/20 1.00
RAB9A P51151 4/20 0.72
KMT2A Q03164 2/20 0.72
MEN1 O00255 1/20 0.72
NPC1 O15118 3/20 0.71
F12 P00748 1/20 0.67
ADORA3 P0DMS8 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4971958 0.91 MAOB (0.83) MAOBMAOARAB9ANPC1F12
SCHEMBL28649035 0.91 MAOB (0.83) MAOBMAOARAB9ANPC1F12
SCHEMBL13936231 0.85 MAOB (1.00) MAOBMAOARAB9ANPC1F12
SCHEMBL11462954 0.85 MAOB (0.91) MAOBMAOARAB9ANPC1F12
SCHEMBL12869894 0.82 MAOB (0.70) MAOBMAOARAB9AKMT2AMEN1
SCHEMBL831792 0.81 MAOB (1.00) MAOBMAOARAB9ANPC1F12
SCHEMBL4969156 0.80 MAOB (0.76) MAOBMAOARAB9ANPC1F12
SCHEMBL4972712 0.80 MAOB (1.00) MAOBMAOAF12
SCHEMBL6228552 0.79 MAOB (1.00) MAOBMAOARAB9AKMT2AMEN1
SCHEMBL28014856 0.79 MAOB (0.65) MAOBMAOARAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008104925-A1 CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES UNIVERSIDADE DO PORTO (PT) 2008-09-04 WO claimed
CN-113461648-A Coumarin 3-formamide neuraminidase inhibitor and preparation method and application thereof 上海应用技术大学 2021-10-01 CN disclosed
WO-2008104925-A1 CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES UNIVERSIDADE DO PORTO (PT) 2008-09-04 WO disclosed