SCHEMBL4973239

SCHEMBL4973239

FC(F)c1ccccc1I

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.31
IDO1 P14902 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448567 1.00 TAAR1 (0.31) TAAR1IDO1TRPA1
SCHEMBL1538924 0.78 GABRA1 (0.35) IDO1TRPA1
SCHEMBL24597112 0.77
SCHEMBL24355265 0.77
SCHEMBL4088437 0.77 TAAR1 (0.33) TAAR1IDO1
SCHEMBL24803974 0.75 PDPK1 (0.31)
SCHEMBL24597274 0.75 CYP1A2 (0.33)
SCHEMBL2306254 0.75 S1PR1 (0.38)
SCHEMBL11606150 0.74 CYP3A4 (0.44) TAAR1IDO1
SCHEMBL28812085 0.74 TSHR (0.38) TAAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117185897-A Synthesis method of difluoromethyl halobenzene 上海泰坦科技股份有限公司 2023-12-08 CN disclosed
EP-1989191-A1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE Boehringer Ingelheim International GmbH (DE) 2008-11-12 EP disclosed
WO-2007093610-A1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-08-23 WO disclosed
CN-1220666-C Monomer containing electron drawing group and electron donating group and polymer and proton conductive membrane containing same JSR CORP (JP) 2005-09-28 CN disclosed
CN-1379009-A Monomer containing electron drawing group and electron donating group and polymer and proton conductive membrane containing same JSR CORP (JP) 2002-11-13 CN disclosed