Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30238408 | 0.81 | L3MBTL1 (0.46) | L3MBTL1TRPV1KDM4EKMT2ACCNC | |
| SCHEMBL25251294 | 0.77 | L3MBTL1 (0.46) | L3MBTL1KDM4EKMT2ADGAT1PARP1 | |
| SCHEMBL27096681 | 0.77 | KDM4E (0.43) | L3MBTL1KDM4EDGAT1PARP1AKT1 | |
| SCHEMBL30881695 | 0.77 | KDM4E (0.43) | L3MBTL1KDM4EDGAT1PARP1AKT1 | |
| SCHEMBL15991433 | 0.73 | SIRT3 (0.43) | L3MBTL1KDM4ECCNCCDK8DGAT1 | |
| SCHEMBL28182603 | 0.72 | KMT2A (0.38) | L3MBTL1KDM4EKMT2AALDH1A1CDC7 | |
| SCHEMBL27968402 | 0.71 | PARP1 (0.43) | KDM4EDGAT1PARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31156314 | 0.71 | PARP1 (0.43) | KDM4EDGAT1PARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27722750 | 0.71 | PARP1 (0.49) | KDM4EPARP1AURKAALDH1A1SMN1; SMN2 | |
| SCHEMBL45808 | 0.71 | L3MBTL1 (0.41) | L3MBTL1KDM4EPARP1AURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124614-A1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-10-16 | — | — | WO | disclosed |