SCHEMBL4974265

SCHEMBL4974265

C=CC(=O)NCCCN(CCC)CCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.64
ZDHHC2 Q9UIJ5 3/20 0.64
ALDH1A1 P00352 2/20 0.47
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
DNM1 Q05193 1/20 0.38
GAA P10253 1/20 0.38
KDM5A P29375 3/20 0.37
FAAH O00519 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EPHX1 P07099 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279433 0.97 ZDHHC20 (0.62) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL1072097 0.97 ZDHHC20 (0.68) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL4979120 0.95 ZDHHC20 (0.67) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL4976649 0.93 ZDHHC20 (0.59) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL2830550 0.92 ZDHHC20 (0.71) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL3278217 0.92 ZDHHC20 (0.71) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL3279527 0.92 ZDHHC20 (0.66) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL2832067 0.90 ZDHHC20 (0.74) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL4975704 0.90 ZDHHC20 (0.59) ZDHHC20ZDHHC2ALDH1A1DRD2DRD4
SCHEMBL2831579 0.90 ZDHHC20 (0.74) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2818505-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-02-01 EP disclosed
EP-2787033-B1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9340663-B2 Rubber composition for tire, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
EP-2818505-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-12-31 EP disclosed
US-20140371372-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-12-18 US disclosed
US-20140323660-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-30 US disclosed
US-8865836-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2787033-A1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2014-10-08 EP disclosed
EP-2543702-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2013-09-11 EP disclosed
US-20130012660-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-10 US disclosed
EP-2543702-A1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2013-01-09 EP disclosed
US-7339005-B2 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-04 US disclosed
US-20040152845-A1 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-05 US disclosed
EP-0334042-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-11-18 EP disclosed
EP-0341496-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-10-20 EP disclosed
US-5219938-A Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-15 US disclosed
US-5189109-A Acrylamide modified; impact strength; automobile tire SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-02-23 US disclosed
US-5128416-A Automobile tire treads SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-07 US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
EP-0334042-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-27 EP disclosed