Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402826 | 0.92 | CYP2C9 (0.47) | CYP2C9 | |
| SCHEMBL10279600 | 0.84 | LMNA (0.45) | — | |
| SCHEMBL4975360 | 0.83 | CYP2C9 (0.56) | CYP2C9 | |
| SCHEMBL4970076 | 0.77 | CYP2C9 (0.53) | CYP2C9 | |
| SCHEMBL4968884 | 0.77 | CYP2C9 (0.51) | CYP2C9 | |
| SCHEMBL13643827 | 0.76 | CYP2C9 (0.63) | CYP2C9 | |
| SCHEMBL399791 | 0.76 | CYP2C9 (0.61) | CYP2C9 | |
| SCHEMBL1015289 | 0.76 | CYP2C9 (0.56) | CYP2C9 | |
| SCHEMBL399547 | 0.75 | CYP2C9 (0.55) | CYP2C9 | |
| SCHEMBL4903090 | 0.75 | CYP2C9 (0.62) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957461-A1 | BISAMIDE INHIBITORS OF HEDGEHOG SIGNALING | Genentech, Inc. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007059157-A1 | BISAMIDE INHIBITORS OF HEDGEHOG SIGNALING | GENENTECH, INC. (US) | 2007-05-24 | — | — | WO | disclosed |