Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | AHR | P35869 | 4/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.65 |
| ▸ | ITGAL | P20701 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | ADK | P55263 | 1/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440252 | 0.90 | USP2 (1.00) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL50566 | 0.90 | USP2 (1.00) | USP2GAAALOX15RAD51NPSR1 | |
| Indole SCHEMBL10638278 | 0.88 | AHR (0.77) | USP2GAAALOX15RAD51NPSR1 | |
| Water SCHEMBL28220544 | 0.88 | USP2 (0.95) | USP2GAAALOX15RAD51NPSR1 | |
| Indole SCHEMBL1979308 | 0.88 | AHR (0.77) | USP2GAAALOX15RAD51NPSR1 | |
| Bromide SCHEMBL6029763 | 0.88 | USP2 (0.95) | USP2GAAALOX15RAD51NPSR1 | |
| Hydrochloric Acid SCHEMBL4718421 | 0.88 | USP2 (0.95) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL5447196 | 0.86 | TYR (0.84) | USP2GAAALOX15RAD51NPSR1 | |
| Indole SCHEMBL1071071 | 0.82 | AHR (0.74) | USP2GAAALOX15RAD51NPSR1 | |
| Indole SCHEMBL6386255 | 0.81 | AHR (0.90) | USP2GAAALOX15RAD51NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978805-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085660-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-08-02 | — | — | WO | disclosed |
| EP-0619805-A1 | INDOLE DERIVATIVES | PFIZER HOSPITAL PRODUCTS, INC. (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993011106-A1 | INDOLE DERIVATIVES | PFIZER, INC. (US) | 1993-06-10 | — | — | WO | disclosed |