SCHEMBL4975232

SCHEMBL4975232

O=C(O)CC(O)(CC(=O)OC(CC(=O)O)(CC(=O)O)C(=O)O)C(=O)O.[NaH].[NaH].[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 4/20 0.33
LMNA P02545 3/20 0.33
TSHR P16473 2/20 0.33
MAPT P10636 2/20 0.33
ALOX15 P16050 1/20 0.33
SLC13A5 Q86YT5 7/20 0.33
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
CYP2D6 P10635 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
ACLY P53396 3/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
CPT2 P23786 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1578237 1.00 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL2289694 1.00 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL2235360 1.00 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL1173001 1.00 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
Hydrogen Peroxide SCHEMBL29082273 1.00 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL9125731 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT
Water SCHEMBL8440717 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT
Water SCHEMBL789158 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL11060181 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL10561448 0.98 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101556281-B Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH 2012-12-05 CN claimed
CN-101556281-A Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH (CN) 2009-10-14 CN claimed
CN-110381986-B Truncated von willebrand factor polypeptides for extravascular administration to treat or prevent coagulation disorders 康诺贝林伦瑙有限公司 2023-08-18 CN disclosed
CN-114246953-A anti-cMet antibody drug conjugates and methods of use thereof 艾伯维生物制药股份有限公司 2022-03-29 CN disclosed
CN-114177308-A anti-cMet antibody drug conjugates and methods of use thereof 艾伯维生物制药股份有限公司 2022-03-15 CN disclosed
CN-109562189-B anti-cMet antibody drug conjugates and methods of use thereof 艾伯维生物制药股份有限公司 2021-12-31 CN disclosed
CN-113226324-A Thiocarbamate derivatives as A2A inhibitors, pharmaceutical compositions thereof and combinations with anticancer agents ITEOS比利时公司 2021-08-06 CN disclosed
CN-113164462-A Use of inhibitors of ENT family transporters in cancer therapy and combinations thereof with adenosine receptor antagonists ITEOS比利时公司 2021-07-23 CN disclosed
CN-112955179-A Antagonistic anti-tumor necrosis factor receptor superfamily polypeptides 综合医院公司 2021-06-11 CN disclosed
CN-112020648-A Articles and methods for cancer-directed personalized therapy 赫斯佩瑞克斯股份公司 2020-12-01 CN disclosed
EP-3681467-A2 COMPOSITIONS COMPRISING LESPEDEZA PLANT EXTRACT Clariant International Ltd (CH) 2020-07-22 EP disclosed
CN-106456833-B Cornea bionic biological material: vitrified collagen-cyclodextrin implants 约翰霍普金斯大学 2020-01-10 CN disclosed
WO-2018127612-A2 COMPOSITIONS COMPRISING LESPEDEZA PLANT EXTRACT CLARIANT INTERNATIONAL LTD (CH) 2018-07-12 WO disclosed
CN-103220916-B Cheese and retort pouch food using cheese MEIJI CO.,LTD. (JP) 2015-11-25 CN disclosed
CN-103220916-A Cheese and retort pouch food using cheese MEIJI CO LTD 2013-07-24 CN disclosed
CN-101556281-B Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH 2012-12-05 CN disclosed
CN-101556281-A Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH (CN) 2009-10-14 CN disclosed
EP-1993504-A2 WET WIPES WITH NATURAL ANTIMICROBIAL AGENTS The Procter & Gamble (US) 2008-11-26 EP disclosed
CN-101115769-A Interferon-alpha polypeptides and conjugates ROCHE PALO ALTO LLC (US) 2008-01-30 CN disclosed
WO-2007069214-A2 WET WIPES WITH NATURAL ANTIMICROBIAL AGENTS THE PROCTER & GAMBLE COMPANY (US) 2007-06-21 WO disclosed