⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665831 | 0.80 | — | — | |
| SCHEMBL1050009 | 0.77 | — | — | |
| SCHEMBL3672467 | 0.76 | CA1 (0.41) | — | |
| SCHEMBL7446572 | 0.75 | RELA (0.47) | — | |
| SCHEMBL9665524 | 0.73 | CA1 (0.45) | — | |
| SCHEMBL779252 | 0.73 | — | — | |
| SCHEMBL2048942 | 0.73 | MEN1 (0.46) | — | |
| SCHEMBL3667558 | 0.73 | GRIA1 (0.39) | — | |
| SCHEMBL28017 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL17258785 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024514-B | Aminodithioformate compound, preparation method thereof, pharmaceutical composition and application thereof | 北京大学 | 2022-02-15 | — | — | CN | claimed |
| CN-113024514-A | Aminodithioformate compound, preparation method thereof, pharmaceutical composition and application thereof | 北京大学 | 2021-06-25 | — | — | CN | claimed |
| US-8461328-B2 | Tricyclic heterocyclic compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2013-06-11 | — | — | US | claimed |
| WO-2013007768-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF AS JAK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | claimed |
| EP-2523957-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F. Hoffmann-La Roche AG (CH) | 2012-11-21 | — | — | EP | claimed |
| US-20110201593-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2011-08-18 | — | — | US | claimed |
| WO-2011086053-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2011-07-21 | — | — | WO | claimed |
| US-7910743-B2 | Compounds, compositions and methods | CYTOKINETICS, INC. (US) | 2011-03-22 | — | — | US | claimed |
| CN-101648947-A | 4-(n-phenylamino)-quinazolines / quinolines as tyrosine kinase inhibitors | BOEHRINGER INGELHEIM PHARMA DE | 2010-02-17 | — | — | CN | claimed |
| US-20090324511-A1 | Compounds, Compositions and Methods | CYTOKINETICS, INC. | 2009-12-31 | — | — | US | claimed |
| US-20090304631-A1 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION | 2009-12-10 | — | — | US | claimed |
| EP-2029153-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | Phenomix Corporation (US) | 2009-03-04 | — | — | EP | claimed |
| WO-2007089618-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-08-09 | — | — | WO | claimed |
| US-20070066626-A1 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED | 2007-03-22 | — | — | US | claimed |
| CN-1642552-A | 4- (N-phenylamino) -quinazolines/quinolines as tyrosine kinase inhibitors | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-07-20 | — | — | CN | claimed |
| EP-4398916-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES | Orchard Therapeutics (Europe) Limited (GB) | 2024-07-17 | — | — | EP | disclosed |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-4418037-A | PYROGALLOL DERIVATIVE STORAGE STABILIZER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-29 | — | — | US | disclosed |
| US-4350692-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4157915-A | (2-BENZENESULFONYL)-ETHOXYCARBONYLAMINO-ANILINE COMPOUND AS THE PRECURSOR | FUJI PHOTO FILM CO., LTD. (JP) | 1979-06-12 | — | — | US | disclosed |