Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339207 | 0.91 | ESR1 (0.33) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL2417003 | 0.80 | ESR1 (0.57) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL237249 | 0.80 | ESR1 (0.57) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL29020575 | 0.79 | ESR1 (0.59) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL6011986 | 0.79 | ESR1 (0.59) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL1790505 | 0.79 | ESR1 (0.46) | ESR1ESR2ALDH1A1CYP3A4KDM4E | |
| Bisphenol A SCHEMBL2128016 | 0.78 | ESR1 (0.52) | ESR1ESR2ALDH1A1CYP3A4LMNA | |
| Phenol SCHEMBL8854471 | 0.77 | TDP1 (0.41) | ESR1ESR2ALDH1A1CYP3A4KDM4E | |
| SCHEMBL4313242 | 0.76 | ESR1 (0.53) | ESR1ESR2ALDH1A1CYP3A4KIF11 | |
| SCHEMBL2416999 | 0.75 | ESR1 (0.60) | ESR1ESR2ALDH1A1CYP3A4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335716-B1 | Ethylene (co)polymers and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |