Phenol

Phenol

SCHEMBL8854471

OCC(CO)(CO)COP(O)O.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GLA P06280 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
KDM4E B2RXH2 2/20 0.40
POLB P06746 1/20 0.40
ESR1 P03372 5/20 0.32
ESR2 Q92731 5/20 0.32
HIF1A Q16665 2/20 0.32
LMNA P02545 2/20 0.32
CYP1A2 P05177 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL9494536 0.82 DGAT1 (0.38) TDP1CA12CA1CA2GLA
Phenol SCHEMBL8854476 0.80 CA12 (0.52) TDP1CA12CA1CA2GLA
Bisphenol A SCHEMBL2128016 0.80 ESR1 (0.52) ESR1ESR2LMNASLC6A2SLC6A3
SCHEMBL518608 0.79 ALDH1A1 (0.32) HIF1AMAPK1ALDH1A1CYP3A4TP53
SCHEMBL11879928 0.77 ALDH1A1 (0.30) ALDH1A1
Phenol SCHEMBL8029599 0.77 CA12 (0.61) TDP1CA12CA1CA2GLA
SCHEMBL9719748 0.77 ALDH1A1 (0.30) ALDH1A1
Phenol SCHEMBL10790520 0.77 CA12 (0.61) TDP1CA12CA1CA2GLA
SCHEMBL4975498 0.77 ESR1 (0.39) KDM4EPOLBESR1ESR2HIF1A
Hydrochloric Acid SCHEMBL11678985 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5683628-A P-BIS((METH)ACRYLOYLOXYALKYLTHIO)XYLYLENE DERIVATIVES SEIKO EPSON CORP. (JP) 1997-11-04 US disclosed
EP-0708164-A2 Photochromic composition and photochromic resin obtainable by using the same SEIKO EPSON CORPORATION (JP) 1996-04-24 EP disclosed