SCHEMBL4975718

SCHEMBL4975718

CC(O)C(=O)ONC(N)=O.[NaH]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
CA14 Q9ULX7 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685110 0.98 TP53 (0.35) TP53CA14SMN1; SMN2
Ammonia Solution, Strong SCHEMBL10777596 0.95 TP53 (0.33) TP53CA14SMN1; SMN2
SCHEMBL709897 0.81 TP53 (0.33) TP53CA14SMN1; SMN2
SCHEMBL27975998 0.80 CA14 (0.34) CA14SMN1; SMN2
SCHEMBL28996658 0.79 CA14 (0.31) CA14
SCHEMBL28229503 0.77 SLC7A5 (0.31) CA14
SCHEMBL27703328 0.77 TSHR (0.33)
SCHEMBL28306915 0.76 NOS1 (0.36)
SCHEMBL3233916 0.75
SCHEMBL29286374 0.74 SMN1; SMN2 (0.36) CA14SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101090706-B Cosmetic and/or dermatological composition for sensitive skin OREAL 2013-05-29 CN disclosed
EP-1973519-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES Symrise GmbH & Co. KG (DE) 2008-10-01 EP disclosed
CN-101090706-A Cosmetic and/or dermatological composition for sensitive skin OREAL (FR) 2007-12-19 CN disclosed
WO-2007077260-A1 FORMULATIONS OF LOW OIL CONTENT COMPRISING DIPHENYLMETHANE DERIVATIVES SYMRISE GMBH & CO. KG (DE) 2007-07-12 WO disclosed