SCHEMBL497611

SCHEMBL497611

O=C1c2c(O)ccc(O)c2C(=O)c2c(Cl)ccc(Cl)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 3/20 0.54
CSNK2B P67870 3/20 0.54
CSNK2A1 P68400 3/20 0.54
CSNK2A3 Q8NEV1 3/20 0.54
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
MAPT P10636 5/20 0.50
CYP3A4 P08684 5/20 0.50
MAPK1 P28482 5/20 0.50
TDP1 Q9NUW8 5/20 0.50
MAOA P21397 4/20 0.50
HPGD P15428 4/20 0.50
ALDH1A1 P00352 4/20 0.50
USP2 O75604 4/20 0.50
ALOX15 P16050 4/20 0.50
TP53 P04637 3/20 0.50
THRB P10828 3/20 0.50
HSD17B10 Q99714 3/20 0.50
RECQL P46063 3/20 0.50
KDM4E B2RXH2 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887225 1.00 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL7742020 1.00 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL7738621 1.00 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL10356073 1.00 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL1323063 1.00 CSNK2A2 (0.54) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL11852041 0.91 CSNK2A2 (0.47) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL6674009 0.88 CSNK2A2 (0.44) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL9059735 0.88 CSNK2A2 (0.44) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL10356109 0.88 CSNK2A2 (0.77) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL6905105 0.85 MAPT (0.76) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776895-A Preparation method of 1, 4-dihydroxy-5, 8-dichloro anthraquinone 宁波龙欣精细化工有限公司 2024-03-29 CN claimed
CN-109836343-B Process for preparing phenylaminohydroxyanthraquinones 朗盛德国有限责任公司 2022-02-11 CN claimed
EP-3489218-B1 METHOD FOR THE PRODUCTION OF PHENYLAMINOHYDROXYANTHRACHINONES LANXESS DEUTSCHLAND GMBH (DE) 2021-06-30 EP claimed
US-20190161617-A1 METHOD FOR PREPARING PHENYLAMINOHYDROXYANTHRAQUINONES LANXESS DEUTSCHLAND GMBH (DE) 2019-05-30 US claimed
EP-3489218-A1 METHOD FOR THE PRODUCTION OF PHENYLAMINOHYDROXYANTHRACHINONES LANXESS Deutschland GmbH (DE) 2019-05-29 EP claimed
EP-3489217-A1 METHOD FOR THE PRODUCTION OF PHENYLAMINOHYDROXYANTHRACHINONES LANXESS Deutschland GmbH (DE) 2019-05-29 EP claimed
EP-1074586-B1 Process for the preparation of arylaminohydroxyanthraquinones BAYER CHEMICALS AG (DE) 2004-05-19 EP claimed
US-6420576-B1 AMINATION OF ANTHRAQUINONE WITH AMINE IN SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US claimed
EP-1074586-A1 Process for the preparation of arylaminohydroxyanthraquinones BAYER AG (DE) 2001-02-07 EP claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
US-5064442-A HAIR DYES L'OREAL (FR) 1991-11-12 US claimed
US-4645626-A Process for the production of quinizarine derivatives which are disubstituted in the 5- and 8-positions by hydroxyl or chlorine CIBA-GEIGY AG (CH) 1987-02-24 US claimed
US-4602913-A Use of hydroxyanthraquinones for the coloration of human keratin fibres L'OREAL (FR) 1986-07-29 US claimed
EP-0038777-B1 PROCESS FOR THE PREPARATION OF OH OR CHLORO DERIVATIVES OF QUINIZARINE BISUBSTITUTED IN POSITION 5 AND 8 CIBA-GEIGY AG (CH) 1983-10-05 EP claimed
EP-0038777-A1 Process for the preparation of OH or chloro derivatives of quinizarine bisubstituted in position 5 and 8 CIBA-GEIGY AG (CH) 1981-10-28 EP claimed
JP-7179389-A None JP disclosed
CN-117776895-B Preparation method of 1, 4-dihydroxy-5, 8-dichloro anthraquinone 宁波龙欣精细化工有限公司 2025-08-29 CN disclosed
US-4115412-A TRANSFER PRINTING, ANTHRAQUINONE DYES BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-3939113-A ANTHRAQUINONE DYES CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed