Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4977470 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL4332470 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL4540519 | 0.80 | — | — | |
| Bromide SCHEMBL7889940 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3925409 | 0.75 | TDP1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4974095 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1844551 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5513480 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27760524 | 0.74 | — | — | |
| SCHEMBL5365763 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397394-B1 | POLYETHYLENE RESINS | UNIVATION TECH LLC (US) | 2012-05-23 | — | — | EP | disclosed |
| US-7459509-B2 | Polyethylene resins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20080039606-A9 | Polyethylene resins | BARRY DAVID B | 2008-02-14 | — | — | US | disclosed |
| US-20070173623-A1 | Polyethylene resins | UNIVATION TECHNOLOGIES, LLC | 2007-07-26 | — | — | US | disclosed |
| US-7199195-B2 | Polyethylene resins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-04-03 | — | — | US | disclosed |
| EP-1397394-A4 | POLYETHYLENE RESINS | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20040186251-A1 | Polyethylene resine | UNIVATION TECHNOLOGIES, LLC | 2004-09-23 | — | — | US | disclosed |
| EP-1397394-A1 | POLYETHYLENE RESINS | Exxonmobil Chemical Patents Inc. (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002090393-A1 | POLYETHYLENE RESINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-11-14 | — | — | WO | disclosed |