Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361008 | 0.83 | DHODH (0.41) | SMN1; SMN2PKMDHODH | |
| SCHEMBL535475 | 0.83 | DHODH (0.41) | SMN1; SMN2PKMDHODH | |
| SCHEMBL23249646 | 0.82 | DHODH (0.41) | SMN1; SMN2PKMDHODH | |
| Hydrochloric Acid SCHEMBL23754596 | 0.82 | DHODH (0.41) | SMN1; SMN2PKMDHODH | |
| SCHEMBL29215123 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27824027 | 0.77 | DHODH (0.35) | KDM4ESMN1; SMN2MEN1KMT2ATDP1 | |
| Toluene SCHEMBL28941923 | 0.77 | DHODH (0.44) | KDM4EALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL4976151 | 0.76 | MEN1 (0.37) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1198603 | 0.76 | L3MBTL1 (0.35) | KDM4EMEN1KMT2APOLBRECQL | |
| SCHEMBL29920957 | 0.76 | L3MBTL1 (0.35) | KDM4EMEN1KMT2APOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339057-B2 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1549643-B1 | METHOD FOR PREPARING FUSED OXAZINONES FROM ORTHO-AMINO AROMATIC CARBOXYLIC ACID AND A CARBOXYLIC ACID IN THE PRESENCE OF A SULFONYL CHLORIDE AND PYRIDINE | DU PONT (US) | 2007-08-29 | — | — | EP | disclosed |
| US-20050215785-A1 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | FMC CORPORATION | 2005-09-29 | — | — | US | disclosed |
| EP-1549643-A2 | METHOD FOR PREPARING FUSED OXAZINONES FROM ORTHO-AMINO AROMATIC CARBOXYLIC ACID AND A CARBOXYLIC ACID IN THE PRESENCE OF A SULFONYL CHLORIDE AND PYRIDINE | E.I. du Pont de Nemours and Company (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011447-A2 | METHOD FOR PREPARING FUSED OXAZINONES FROM ORTHO-AMINO AROMATIC CARBOXYLIC ACID AND A CARBOXYLIC ACID IN THE PRESENCE OF A SULFONYL CHLORIDE AND PYRIDINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215785-A1 | Method for preparing fused oxazinones from ortho-amino aromatic carboxylic acid and carboxylic acid in the presence of a sulfonyl chloride and pyridine | OXGR1, OXSR1, OXER1 | KDM4E 1201/4885ALDH1A1 823/4885SMN1; SMN2 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.