Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13230686 | 0.87 | TSHR (0.44) | USP2HTTALDH1A1TSHRCYP3A4 | |
| SCHEMBL11035573 | 0.86 | CA1 (0.42) | ALDH1A1TSHRCA1CA2CA7 | |
| SCHEMBL1346255 | 0.81 | LPAR5 (0.30) | LPAR5 | |
| SCHEMBL601010 | 0.76 | TSHR (0.57) | USP2HTTALDH1A1TSHRCYP3A4 | |
| SCHEMBL13230693 | 0.76 | TSHR (0.57) | USP2HTTALDH1A1TSHRCYP3A4 | |
| SCHEMBL18961286 | 0.76 | TSHR (0.57) | USP2HTTALDH1A1TSHRCYP3A4 | |
| SCHEMBL18784691 | 0.76 | TSHR (0.57) | USP2HTTALDH1A1TSHRCYP3A4 | |
| SCHEMBL2010197 | 0.76 | — | — | |
| SCHEMBL8597422 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL2113973 | 0.74 | TSHR (0.53) | USP2HTTALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015272-A1 | Polyurethane Foam | FRITZ NAUER AG (CH) | 2008-01-17 | — | — | US | disclosed |