Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.63 |
| ▸ | EGFR | P00533 | 4/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975906 | 0.89 | IGF1R (0.60) | IGF1REGFRERBB2 | |
| SCHEMBL2953563 | 0.87 | IGF1R (0.78) | IGF1REGFRERBB2 | |
| SCHEMBL2963626 | 0.82 | IGF1R (0.76) | IGF1REGFRERBB2 | |
| SCHEMBL2967342 | 0.81 | IGF1R (0.75) | IGF1REGFRERBB2 | |
| SCHEMBL2967885 | 0.81 | IGF1R (0.77) | IGF1REGFRERBB2 | |
| SCHEMBL16762565 | 0.78 | IGF1R (0.77) | IGF1REGFRERBB2 | |
| SCHEMBL2967021 | 0.78 | IGF1R (1.00) | IGF1REGFRERBB2 | |
| SCHEMBL2967017 | 0.78 | IGF1R (1.00) | IGF1REGFRERBB2 | |
| SCHEMBL2967454 | 0.78 | IGF1R (0.69) | IGF1REGFRERBB2 | |
| SCHEMBL2960985 | 0.77 | IGF1R (0.68) | IGF1REGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973917-A2 | PROTEIN KINASE INHIBITORS | Abbott Laboratories (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079164-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2007-07-12 | — | — | WO | disclosed |