Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.60 |
| ▸ | EGFR | P00533 | 9/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977273 | 0.89 | IGF1R (0.63) | IGF1REGFRERBB2 | |
| SCHEMBL2953563 | 0.85 | IGF1R (0.78) | IGF1REGFRERBB2 | |
| SCHEMBL2969096 | 0.82 | IGF1R (0.77) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2961009 | 0.81 | IGF1R (0.74) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2967885 | 0.78 | IGF1R (0.77) | IGF1REGFRERBB2 | |
| SCHEMBL2962013 | 0.78 | IGF1R (0.63) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL4979657 | 0.78 | IGF1R (0.48) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2967342 | 0.77 | IGF1R (0.75) | IGF1REGFRERBB2 | |
| SCHEMBL16762565 | 0.76 | IGF1R (0.77) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2956394 | 0.76 | IGF1R (0.75) | IGF1REGFRERBB2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973917-A2 | PROTEIN KINASE INHIBITORS | Abbott Laboratories (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079164-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2007-07-12 | — | — | WO | disclosed |