Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067553 | 0.75 | CYP1A2 (0.37) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL2580716 | 0.75 | CYP1A2 (0.37) | CYP1A2CHRM2CYP2D6CHRM1KCNH2 | |
| SCHEMBL1030996 | 0.75 | CYP1A2 (0.37) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL10234483 | 0.75 | CYP1A2 (0.37) | CYP1A2CHRM2CYP2D6CHRM1KCNH2 | |
| SCHEMBL21810986 | 0.75 | CHRM2 (0.39) | CYP1A2CHRM2CYP2D6CHRM1KCNH2 | |
| SCHEMBL5083323 | 0.75 | CYP1A2 (0.37) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL16974430 | 0.74 | GRM2 (0.40) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL10876420 | 0.73 | CYP1A2 (0.36) | CYP1A2CHRM2CYP2D6CHRM1KCNH2 | |
| SCHEMBL17976970 | 0.73 | CYP1A2 (0.36) | CYP1A2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL10876431 | 0.73 | CYP1A2 (0.36) | CYP1A2CHRM2CYP2D6CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370773-B | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD | 2014-04-09 | — | — | CN | disclosed |
| CN-101370773-A | Cycloalkanecarboxamide derivative and method for producing same | SEIKAGAKU KOGYO CO LTD (JP) | 2009-02-18 | — | — | CN | disclosed |
| EP-1973917-A2 | PROTEIN KINASE INHIBITORS | Abbott Laboratories (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007079164-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2007-07-12 | — | — | WO | disclosed |