SCHEMBL2067553

SCHEMBL2067553

CCC(N)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
SHBG P04278 1/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39548 0.80 CYP1A2 (0.39) CYP1A2SHBG
SCHEMBL5083323 0.79 CYP1A2 (0.37) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL1030996 0.79 CYP1A2 (0.37) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL3000331 0.78 CYP1A2 (0.40) CYP1A2SHBG
SCHEMBL17976970 0.77 CYP1A2 (0.36) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL4189609 0.76 SIGMAR1 (0.36) LMNASMN1; SMN2SIGMAR1
SCHEMBL1900863 0.76 SIGMAR1 (0.36) LMNASMN1; SMN2SIGMAR1
SCHEMBL13640032 0.76 CYP1A2 (0.33) CYP1A2
SCHEMBL4977291 0.75 CYP1A2 (0.34) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL17337998 0.74 SIGMAR1 (0.34) LMNASMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286657-A Continuous production method of hydroxymethyl phosphonate 湖北理工学院 2022-11-04 CN claimed
US-9187504-B2 Method of making hydroxymethylphosphonate ICL-IP AMERICA INC. (US) 2015-11-17 US claimed
EP-2376507-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES ICL IP AMERICA INC (US) 2013-05-15 EP claimed
US-8198341-B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. (US) 2012-06-12 US claimed
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom STOWELL JEFFREY K 2011-10-20 US claimed
EP-2376507-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM ICL-IP America Inc. (US) 2011-10-19 EP claimed
WO-2010080425-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM SUPRESTA LLC. (US) 2010-07-15 WO claimed
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. 2010-06-24 US claimed
EP-0676429-B1 Composition for urethane-based plastic lens MITSUI CHEMICALS INC (JP) 2000-12-27 EP claimed
CN-114269735-B Dihydro-or tetrahydroquinazoline compound, intermediate thereof, preparation method and application 南京创济生物医药有限公司 2024-02-23 CN disclosed
CN-115703855-A Catalyst system for C4 liquefied petroleum gas cationic polymerization and polybutene production method 南京中科康润新材料科技有限公司 2023-02-17 CN disclosed
WO-2023016561-A1 CATALYST SYSTEM FOR CATIONIC POLYMERIZATION OF C4 LIQUEFIED PETROLEUM GAS AND POLYBUTYLENE PRODUCTION METHOD 南京中科康润新材料科技有限公司 2023-02-16 WO disclosed
CN-115286657-A Continuous production method of hydroxymethyl phosphonate 湖北理工学院 2022-11-04 CN disclosed
CN-107383093-B Hydroxymethylphosphonate, compositions, polyurethane foams, and articles ICL-IP美国有限公司 2021-07-16 CN disclosed
US-20070241313-A1 polymerizing a polymerization raw material in contact with polarizing film; raw material composition contains as one main component an isocyanated or isothiocyanated compound which reacts with the hydroxyl of polyvinyl alcohol resin of polarizing film to form a urethane bond or thiourethane bond SUNLUX CO., LTD. (JP) 2007-10-18 US disclosed
EP-1739462-A1 POLARIZING PLASTIC OPTICAL DEVICE AND PROCESS FOR PRODUCING THE SAME Sunlux Co., Ltd. (JP) 2007-01-03 EP disclosed
EP-0676429-B1 Composition for urethane-based plastic lens MITSUI CHEMICALS INC (JP) 2000-12-27 EP disclosed
US-5693738-A REACTING AN ISOCYANATE AND/OR AN ISOTHIOCYANATE COMPOUND WITH A HYDROXYL AND/OR MERCAPTO-CONTAINING COMPOUND IN THE PRESENCE OF A COMPLEX OF A TERTIARY AMINE AND A LEWIS ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-02 US disclosed
EP-0676429-A2 Composition for urethane-base plastic lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-11 EP disclosed
US-4292196-A Catalyst recovery UOP INC. (US) 1981-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom PFAS, PGM2, NEFM CYP1A2 3928/4885SHBG 2239/4885MEN1 3375/4885
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom PFAS, PGM2, NEFM CYP1A2 3928/4885SHBG 2239/4885MEN1 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.