Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KDM5C | P41229 | 4/20 | 0.52 |
| ▸ | KDM6B | O15054 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4976213 | 0.88 | PHF8 (0.58) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL4980899 | 0.85 | SLC22A6 (0.52) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL4977758 | 0.80 | PHF8 (0.52) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL4977396 | 0.78 | PHF8 (0.57) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL28461081 | 0.78 | PHF8 (0.57) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL3058782 | 0.77 | KDM4E (0.32) | PHF8KDM2AKDM4EKDM5C | |
| SCHEMBL4979704 | 0.75 | SLC22A6 (0.46) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL12967673 | 0.74 | PHF8 (0.52) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| Glycine SCHEMBL16637330 | 0.74 | PHF8 (0.56) | PHF8KDM2AEGLN1KDM4EKDM5C | |
| SCHEMBL4976282 | 0.74 | PHF8 (0.52) | PHF8KDM2AEGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |