Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141199 | 0.85 | NAMPT (0.44) | ALDH1A1LMNASMN1; SMN2RAB9ATSHR | |
| SCHEMBL1367218 | 0.81 | P2RY1 (0.36) | ALDH1A1LMNASMN1; SMN2NOTUMGAA | |
| SCHEMBL1368209 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2KCNN4KCNA5 | |
| SCHEMBL1369059 | 0.79 | ALK (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1368148 | 0.78 | MAP4K4 (0.40) | SMN1; SMN2KCNA5NPC1RAB9AHTT | |
| SCHEMBL12140842 | 0.74 | KDM4C (0.33) | ALDH1A1LMNASMN1; SMN2KCNN4KCNA5 | |
| SCHEMBL1368653 | 0.73 | TAAR1 (0.42) | ALDH1A1LMNASMN1; SMN2KCNA5 | |
| SCHEMBL1370133 | 0.72 | MAPK1 (0.40) | ALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL1369281 | 0.72 | TAAR1 (0.37) | ALDH1A1LMNASMN1; SMN2KCNA5HTT | |
| SCHEMBL1368740 | 0.72 | HCRTR1 (0.40) | ALDH1A1LMNATSHRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993551-A2 | POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007089735-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-08-09 | — | — | WO | claimed |