Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 11/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974922 | 0.88 | PDE10A (0.47) | PDE10AEHMT2EHMT1LMNAKMT2A | |
| SCHEMBL3042943 | 0.82 | PDE10A (0.53) | PDE10APDE3BPDE3ALMNAKMT2A | |
| SCHEMBL11310184 | 0.81 | PDE10A (0.49) | PDE10AEHMT2EHMT1LMNAKMT2A | |
| SCHEMBL3059530 | 0.80 | PDE10A (0.48) | PDE10AEHMT2EHMT1PDE3BPDE3A | |
| SCHEMBL3059781 | 0.80 | PDE10A (0.52) | PDE10APDE3BPDE3ALMNAKMT2A | |
| SCHEMBL3062196 | 0.78 | PDE10A (0.49) | PDE10APDE3BPDE3ALMNAKMT2A | |
| SCHEMBL3051634 | 0.78 | PDE10A (0.54) | PDE10APDE3BPDE3ALMNAKMT2A | |
| Oxalic Acid SCHEMBL11306727 | 0.77 | PDE10A (0.49) | PDE10AEHMT2EHMT1KITLMNA | |
| SCHEMBL3042958 | 0.77 | NTSR1 (0.48) | PDE10APDE3BPDE3ALMNAKMT2A | |
| SCHEMBL3056015 | 0.77 | PDE10A (0.56) | PDE10APDE3BPDE3ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981868-A2 | AMINOPHTHALAZINE DERIVATIVE COMPOUNDS | Pfizer Products Inc. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007085954-A2 | AMINOPHTHALAZINE DERIVATIVE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-08-02 | — | — | WO | claimed |