SCHEMBL4977949

SCHEMBL4977949

CN1CC2CC[C@H]1C2OC(=O)C(O)(c1ccccc1)C1CCCC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.59
CYP2D6 P10635 2/20 0.59
CHRM3 P20309 6/20 0.53
CHRM2 P08172 3/20 0.53
CHRM1 P11229 2/20 0.52
HRH1 P35367 2/20 0.52
KCNH2 Q12809 2/20 0.52
CHRM4 P08173 1/20 0.52
CHRM5 P08912 1/20 0.52
HTR2B P41595 1/20 0.52
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.47
SLC29A1 Q99808 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4977941 1.00 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
SCHEMBL4985771 0.99 CYP1A2 (0.59) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
SCHEMBL4985765 0.99 CYP1A2 (0.59) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
SCHEMBL4184498 0.87 ALDH1A1 (0.67) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
Phencynonate SCHEMBL29506428 0.84 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
Phencynonate SCHEMBL7092217 0.84 ALDH1A1 (0.66) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
Phencynonate SCHEMBL7093102 0.83 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
Phencynonate SCHEMBL29380090 0.83 ALDH1A1 (0.65) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
SCHEMBL4176964 0.83 ALDH1A1 (0.51) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3
SCHEMBL4184606 0.82 CYP1A2 (0.51) ALDH1A1CYP1A2CYP3A4CYP2D6CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1968980-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES, LTD. (IN) 2008-09-17 EP disclosed
WO-2007110782-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2007-10-04 WO disclosed