Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28229337 | 1.00 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL229640 | 0.98 | LMNA (0.58) | LMNAF2TSHRTP53TDP1 | |
| Benzene SCHEMBL28103328 | 0.98 | LMNA (0.58) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL27989259 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL21325951 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL27563421 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL8422588 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL4528180 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL2841791 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 | |
| SCHEMBL27851722 | 0.95 | LMNA (0.56) | LMNAF2TSHRTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976486-A1 | A METHOD OF PRODUCING POROUS MICROPARTICLES | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007086039-A1 | A METHOD OF PRODUCING POROUS MICROPARTICLES | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2007-08-02 | — | — | WO | disclosed |