Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045093 | 1.00 | LTA4H (0.52) | LTA4HADRB1PARP1RENMEN1 | |
| SCHEMBL4288512 | 1.00 | LTA4H (0.52) | LTA4HADRB1PARP1RENMEN1 | |
| SCHEMBL3491740 | 0.88 | LTA4H (0.46) | LTA4HADRB1MEN1KMT2A | |
| SCHEMBL3493396 | 0.86 | TEAD1 (0.46) | PARP1RENMEN1KMT2AL3MBTL1 | |
| SCHEMBL4290785 | 0.85 | PARP1 (0.45) | PARP1RENMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4293711 | 0.85 | PARP1 (0.45) | PARP1RENMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4293709 | 0.85 | PARP1 (0.45) | PARP1RENMEN1KMT2AL3MBTL1 | |
| SCHEMBL3493424 | 0.85 | LTA4H (0.52) | LTA4HADRB1 | |
| SCHEMBL4975002 | 0.84 | MAPT (0.46) | LTA4HADRB1MEN1KMT2A | |
| SCHEMBL15645152 | 0.84 | LTA4H (0.46) | LTA4HADRB1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102456-B | Azaquinazoline inhibitors of atypical protein kinase C | 癌症研究技术有限公司 | 2017-11-14 | — | — | CN | disclosed |
| CN-105102456-A | Azaquinazoline inhibitors of atypical protein kinase C | IGNYTA INC | 2015-11-25 | — | — | CN | disclosed |
| EP-1984355-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | Takeda Pharmaceutical Company Limited (JP) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |
| EP-1539180-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1539180-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018058-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-03-04 | — | — | WO | disclosed |