⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497570 | 0.90 | — | — | |
| SCHEMBL28599960 | 0.88 | — | — | |
| SCHEMBL7007990 | 0.88 | — | — | |
| SCHEMBL28448342 | 0.88 | — | — | |
| SCHEMBL11810823 | 0.88 | — | — | |
| SCHEMBL18741243 | 0.86 | — | — | |
| SCHEMBL8022601 | 0.84 | — | — | |
| SCHEMBL8103295 | 0.80 | — | — | |
| SCHEMBL6836209 | 0.80 | — | — | |
| SCHEMBL10602015 | 0.63 | ESR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681868-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019053026-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-21 | — | — | WO | disclosed |
| EP-2157084-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | KOWA CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-8106053-B2 | 5-phenyl-3-pyridazinone derivative | KOWA COMPANY, LTD. | 2012-01-31 | — | — | US | disclosed |
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100197698-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | KOWA COMPANY, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-2157084-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |