SCHEMBL10602015

SCHEMBL10602015

CC1(c2ccc(C3(C)CCCCC3)cc2)CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4987796 0.90 KMT2A (0.41) ESR1ESR2ALDH1A1L3MBTL1
SCHEMBL11023995 0.88 ALDH1A1 (0.61) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL2841457 0.88 TAAR1 (0.42) ESR1ESR2ALDH1A1L3MBTL1
SCHEMBL14625430 0.88 SLC6A3 (0.52) SLC6A4SLC6A3SLC6A2
SCHEMBL12596028 0.88 SLC6A4 (0.53) SLC6A4SLC6A3SLC6A2
SCHEMBL1516123 0.88 ESR2 (0.61) ESR1ESR2ALDH1A1SLC6A4SLC6A3
SCHEMBL17274037 0.88 ESR1 (0.35) ESR1ESR2ALDH1A1L3MBTL1SLC6A4
SCHEMBL11800829 0.87 KMT2A (0.42) ESR1ESR2
SCHEMBL19382448 0.87 SLC6A4 (0.48) SLC6A4SLC6A3SLC6A2
SCHEMBL2387990 0.87 SLC6A4 (0.48) SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164417-B1 THERMAL RECORDING MATERIAL NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-03-15 EP disclosed
US-4672401-A Heat-sensitive recording materials NIPPON STEEL CHEMICAL CO., LTD. (JP) 1987-06-09 US disclosed
EP-0164417-A1 THERMAL RECORDING MATERIAL NIPPON STEEL CHEMICAL CO., LTD. (JP) 1985-12-18 EP disclosed
US-3959226-A ISOMERIZATION; FRIEDEL-CRAFTS CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-05-25 US disclosed