SCHEMBL4979401

SCHEMBL4979401

CCCCC(F)(F)C(=O)CO[PH](=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 0.44
FAAH O00519 13/20 0.40
CES1 P23141 11/20 0.40
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PLA2G6 O60733 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613477 0.93 CES2 (0.54) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9142904 0.89 CES2 (0.37) CES2FAAHCES1MEN1CYP1A2
SCHEMBL4979395 0.88 CES2 (0.46) CES2FAAHCES1MEN1CYP1A2
SCHEMBL11149563 0.85 CES2 (0.38) CES2FAAHCES1MEN1CYP1A2
SCHEMBL8120581 0.83 CES2 (0.32) CES2
SCHEMBL7613472 0.81 CES2 (0.56) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9162916 0.81 CES2 (0.33) CES2CES1
SCHEMBL7615923 0.80 CES2 (0.36) CES2
SCHEMBL8411176 0.78
SCHEMBL9142899 0.77 CES2 (0.38) CES2FAAHCES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-216778775-U Novel preparation device of (2-oxo-3, 3-difluoro heptyl) dimethyl phosphonate 南京诺希生物科技有限公司 2022-06-21 CN claimed
CN-216778775-U Novel preparation device of (2-oxo-3, 3-difluoro heptyl) dimethyl phosphonate 南京诺希生物科技有限公司 2022-06-21 CN disclosed
EP-1981867-A2 METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE R-Tech Ueno, Ltd. (JP) 2008-10-22 EP disclosed
WO-2007091697-A2 METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE R-TECH UENO, LTD. (JP) 2007-08-16 WO disclosed
EP-0643051-B1 Process for Producing Alfa, Beta-Unsaturated Ketones R TECH UENO LTD (JP) 2000-01-26 EP disclosed
EP-0507625-B1 Method of producing alpha, beta unsaturated ketolactones R TECH UENO LTD (JP) 1996-08-28 EP disclosed
US-5468880-A Method of producing α, β-unsaturated ketones KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1995-11-21 US disclosed
EP-0643051-A1 PROCESS FOR PRODUCING $g(a),$g(b)-UNSATURATED KETONE KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1995-03-15 EP disclosed
US-5229529-A Method of producing α,β-unsaturated ketolactones R-TECH UENO LTD. (JP) 1993-07-20 US disclosed
EP-0507625-A1 Method of producing alpha, beta unsaturated ketolactones R-TECH UENO LTD. (JP) 1992-10-07 EP disclosed