Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423898 | 0.96 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1CNR1 | |
| SCHEMBL2422267 | 0.93 | MAPK9 (0.58) | MAPK9MAPK10KMT2AMEN1CNR1 | |
| SCHEMBL2423345 | 0.90 | MEN1 (0.47) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL2423715 | 0.89 | MEN1 (0.47) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL6431835 | 0.89 | MEN1 (0.55) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL7444767 | 0.87 | MEN1 (0.45) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL2426717 | 0.85 | CYP1A2 (0.45) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL2420394 | 0.84 | CYP1A2 (0.46) | MAPK9MAPK10KMT2AMEN1LMNA | |
| SCHEMBL2423150 | 0.84 | MAPK9 (0.58) | MAPK9MAPK10KMT2AMEN1CNR1 | |
| SCHEMBL27494340 | 0.82 | MAPK9 (0.42) | MAPK9MAPK10KMT2AMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |