Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423345 | 0.97 | MEN1 (0.47) | MEN1KMT2AMAPK9MAPK10THRB | |
| SCHEMBL2422967 | 0.93 | MEN1 (0.51) | MEN1KMT2AMAPK9MAPK10THRB | |
| SCHEMBL2426717 | 0.89 | CYP1A2 (0.45) | MEN1KMT2AMAPK9MAPK10MAPT | |
| SCHEMBL2423715 | 0.89 | MEN1 (0.47) | MEN1KMT2AMAPK9MAPK10THRB | |
| SCHEMBL4979545 | 0.87 | MAPK9 (0.51) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2422267 | 0.86 | MAPK9 (0.58) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL2422166 | 0.84 | CYP1A2 (0.49) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL4992664 | 0.83 | KMT2A (0.47) | MEN1KMT2AMAPK9MAPK10THRB | |
| SCHEMBL6431835 | 0.83 | MEN1 (0.55) | MEN1KMT2AMAPK9MAPK10MAPT | |
| SCHEMBL2423898 | 0.82 | MAPK9 (0.55) | MEN1KMT2AMAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |