SCHEMBL498000

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL497636	0.80	NR1H4 (0.44)	ALDH1A1PDE4BPDE4APDE4CPDE4D
	SCHEMBL20817410	0.79	PDE4B (0.43)	ALDH1A1KDM4EPDE4BPDE4APDE4C
	SCHEMBL29186022	0.77	SLC5A1 (0.46)	ALDH1A1KDM4EHPGDGAASLC5A1
	SCHEMBL1412550	0.76	KDM4E (0.47)	ALDH1A1KDM4EHPGDGAASLC5A1
	SCHEMBL498090	0.76	SLC5A1 (0.46)	ALDH1A1KDM4EHPGDGAASLC5A1
	SCHEMBL25044749	0.75	SLC5A1 (0.46)	ALDH1A1KDM4EHPGDSLC5A1SLC5A2
	SCHEMBL4785326	0.75	CYP19A1 (0.57)	ALDH1A1KDM4EHPGDPOLBLMNA
	SCHEMBL9915129	0.72	KDM4E (0.46)	ALDH1A1KDM4EHPGDGAASLC5A1
	SCHEMBL26034982	0.72	KDM4E (0.46)	ALDH1A1KDM4EHPGDGAASLC5A1
	SCHEMBL1412460	0.72	KDM4E (0.46)	ALDH1A1KDM4EHPGDSLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.