SCHEMBL4980487

SCHEMBL4980487

NC(=O)N(I)C(CCC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIK2 Q13002 1/20 0.43
GRIK3 Q13003 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14729396 0.78 CYP1A2 (0.45) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL30297109 0.77 CYP1A2 (0.46) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28194401 0.76 CYP1A2 (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL16666108 0.76 CYP1A2 (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL22551091 0.76 CYP1A2 (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL8583491 0.74 CYP1A2 (0.50) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL8583489 0.74 CYP1A2 (0.50) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL4994882 0.73 KMT2A (0.44) PMP22
SCHEMBL22551092 0.73 CYP1A2 (0.41) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL31005293 0.72 SLC1A2 (0.44) CYP1A2GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080066741-A1 METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION HUNTER, CHARLES ERIC 2008-03-20 US claimed
US-20240123168-A1 PRODUCT DELIVERY DEVICES AND METHODS MUSTAPHA JIHAD A (US) 2024-04-18 US disclosed
CN-117279681-A Product delivery device and method 呼吸解决方案股份有限公司 2023-12-22 CN disclosed
EP-4255541-A1 PRODUCT DELIVERY DEVICES AND METHODS Breathe Restore, Inc. (US) 2023-10-11 EP disclosed
US-20230181847-A1 PRODUCT DELIVERY DEVICES AND METHODS BREATHE RESTORE INC (US) 2023-06-15 US disclosed
US-11672929-B2 Product delivery devices and methods BREATHE RESTORE, INC. (US) 2023-06-13 US disclosed
WO-2022118225-A1 PRODUCT DELIVERY DEVICES AND METHODS BREATHE RESTORE, INC. (US) 2022-06-09 WO disclosed
US-20220168516-A1 PRODUCT DELIVERY DEVICES AND METHODS BREATHE RESTORE, INC. 2022-06-02 US disclosed
US-9731012-B2 Laser-actuated therapeutic nanoparticles PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-15 US disclosed
US-9554989-B2 Silk reservoirs for drug delivery TRUSTEES OF TUFTS COLLEGE (US) 2017-01-31 US disclosed
US-20150065685-A1 LASER-ACTUATED THERAPEUTIC NANOPARTICLES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2015-03-05 US disclosed
US-20150045764-A1 SILK RESERVOIRS FOR DRUG DELIVERY TRUSTEES OF TUFTS COLLEGE 2015-02-12 US disclosed
EP-2827884-A1 SILK RESERVOIRS FOR DRUG DELIVERY Trustees Of Tufts College (US) 2015-01-28 EP disclosed
WO-2013148158-A1 LASER-ACTUATED THERAPEUTIC NANOPARTICLES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-10-03 WO disclosed
WO-2013142119-A1 SILK RESERVOIRS FOR DRUG DELIVERY TRUSTEES OF TUFTS COLLEGE (US) 2013-09-26 WO disclosed