Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729396 | 0.75 | CYP1A2 (0.45) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL16666108 | 0.73 | CYP1A2 (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28194401 | 0.73 | CYP1A2 (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL22551091 | 0.73 | CYP1A2 (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL4980487 | 0.73 | CYP1A2 (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28155915 | 0.71 | ALOX15 (0.42) | SLC1A3SLC1A2SLC1A1PMP22BLM | |
| SCHEMBL28155913 | 0.71 | ALOX15 (0.42) | SLC1A3SLC1A2SLC1A1PMP22BLM | |
| SCHEMBL8583491 | 0.71 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL8583489 | 0.71 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2800412 | 0.69 | CYP1A2 (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3723728-A1 | INJECTABLE SOLUTION WITH A PH OF 7 COMPRISING AT LEAST ONE BASAL INSULIN WITH A PI OF BETWEEN 5.8 AND 8.5 AND A CO-POLYAMINOACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS | Adocia (FR) | 2020-10-21 | — | — | EP | disclosed |