SCHEMBL498189

SCHEMBL498189

O=C(O)c1ccccc1-c1cc2ccccc2cc1-c1ccccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 5/20 0.54
ALOX15 P16050 1/20 0.54
IDO1 P14902 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX12 P18054 1/20 0.53
FOLH1 Q04609 1/20 0.53
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
SOS1 Q07889 2/20 0.51
MYC P01106 2/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 3/20 0.48
KDM4E B2RXH2 2/20 0.48
LMNA P02545 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12486777 0.92 IDO1 (0.55) HSD17B10ALDH1A1ALOX15IDO1CYP3A4
SCHEMBL2944662 0.89 ALDH1A1 (0.62) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL30888405 0.89 ALDH1A1 (0.62) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL36145 0.86 ALDH1A1 (0.72) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL30028907 0.86 ALDH1A1 (0.72) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL22656935 0.84 SOS1 (0.62) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL10888462 0.84 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL1681943 0.84 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL7579852 0.84 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9
SCHEMBL2830888 0.84 ALDH1A1 (0.68) HSD17B10ALDH1A1ALOX15CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430732-A Catalyst component for propylene polymerization, preparation method thereof, catalyst and application 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-114426599-B Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-11-10 CN claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-110536909-B Method for producing propylene copolymers having a low VOC content 格雷斯公司 2022-08-23 CN claimed
CN-110938161-B Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2022-05-24 CN claimed
CN-114426599-A Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2022-05-03 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113773423-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2021-12-10 CN claimed
CN-113754801-A Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754803-A Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-110938162-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
CN-110938161-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
CN-110938163-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
US-20200071435-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS WITH LOW VOC CONTENT W. R. GRACE & CO.-CONN. 2020-03-05 US claimed
EP-3609931-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS WITH LOW VOC CONTENT W.R. Grace & Co.-Conn. (US) 2020-02-19 EP claimed
WO-2018191212-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS WITH LOW VOC CONTENT W. R. GRACE & CO.-CONN. (US) 2018-10-18 WO claimed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US claimed
US-11993672-B2 Production of high melt flow propylene-based polymer and product from same W.R. GRACE & CO.-CONN. (US) 2024-05-28 US disclosed
US-20100168342-A1 Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168353-A1 Propylene-Based Polymer, Articles, and Process for Producing Same W.R. GRACE & CO.-CONN. 2010-07-01 US disclosed