Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9544973 | 0.90 | KIF11 (0.45) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL25767197 | 0.88 | PDE2A (0.47) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL598661 | 0.86 | KIF11 (0.49) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL16191335 | 0.86 | KIF11 (0.49) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL24270379 | 0.83 | KIF11 (0.46) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL20963009 | 0.83 | KIF11 (0.46) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL31095742 | 0.83 | KIF11 (0.46) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL8968762 | 0.83 | KIF11 (0.50) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL10199855 | 0.83 | PTPN5 (0.49) | KIF11HDAC4HDAC8KDM4EALDH1A1 | |
| SCHEMBL3370465 | 0.83 | KIF11 (0.46) | KIF11HDAC4HDAC8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358411-B2 | Hydrocracking of diphenylalkanes | SHELL OIL COMPANY (US) | 2008-04-15 | — | — | US | claimed |
| EP-1648847-A2 | HYDROCRACKING OF DIPHENYLALKANES | Shell Internationale Research Maatschappij B.V. (NL) | 2006-04-26 | — | — | EP | claimed |
| US-20050049446-A1 | Hydrocracking of diphenylalkanes | SHELL OIL COMPANY | 2005-03-03 | — | — | US | claimed |
| WO-2005005351-A2 | HYDROCRAKING OF DIPHENYLALKANES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2005-01-20 | — | — | WO | claimed |