Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218817 | 0.94 | JAK2 (0.73) | JAK2JAK3 | |
| SCHEMBL217138 | 0.88 | JAK2 (0.82) | JAK2JAK3 | |
| SCHEMBL220017 | 0.83 | JAK3 (0.88) | JAK2JAK3 | |
| SCHEMBL220721 | 0.81 | JAK3 (0.79) | JAK2JAK3 | |
| SCHEMBL5000771 | 0.81 | JAK2 (0.53) | JAK2JAK3 | |
| SCHEMBL4982949 | 0.78 | JAK3 (1.00) | JAK2JAK3 | |
| SCHEMBL251027 | 0.77 | JAK2 (0.51) | JAK2JAK3 | |
| SCHEMBL219030 | 0.76 | JAK2 (0.47) | JAK2JAK3 | |
| SCHEMBL4980198 | 0.75 | JAK2 (0.64) | JAK2JAK3 | |
| SCHEMBL4981256 | 0.75 | JAK2 (1.00) | JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |