Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448297 | 0.85 | ALOX5 (0.51) | ALOX5 | |
| Hydrochloric Acid SCHEMBL4983349 | 0.84 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL4981814 | 0.84 | GRIN2D (0.40) | — | |
| SCHEMBL17887865 | 0.75 | CARM1 (0.51) | SLC1A5GAACARM1PRMT1HTR1A | |
| SCHEMBL4982387 | 0.70 | NR1H4 (0.40) | ALOX5 | |
| SCHEMBL4986163 | 0.70 | ALOX5 (0.56) | ALOX5GAAF2PRSS1PRSS2 | |
| SCHEMBL6682745 | 0.69 | HTR2A (0.38) | — | |
| Hydrochloric Acid SCHEMBL4981825 | 0.69 | NR1H4 (0.40) | ALOX5 | |
| Hydrochloric Acid SCHEMBL4983794 | 0.69 | ALOX5 (0.55) | ALOX5GAAF2PRSS1PRSS2 | |
| SCHEMBL28572476 | 0.68 | BCHE (0.60) | ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351743-B1 | Therapeutic guanidines | WYETH (US) | 2008-04-01 | — | — | US | disclosed |