Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 11/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.35 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989936 | 0.87 | KMT2A (0.45) | SMN1; SMN2OXTRAVPR1AL3MBTL1KMT2A | |
| SCHEMBL4987515 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2OXTRAVPR1AL3MBTL1CHRNB2 | |
| SCHEMBL4988267 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2OXTRAVPR1AL3MBTL1TDP1 | |
| SCHEMBL4990274 | 0.85 | MEN1 (0.38) | SMN1; SMN2OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL4982122 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2OXTRAVPR1AL3MBTL1TDP1 | |
| SCHEMBL14186820 | 0.84 | OXTR (0.41) | SMN1; SMN2OXTRAVPR1AL3MBTL1MEN1 | |
| SCHEMBL4987571 | 0.84 | HTT (0.40) | SMN1; SMN2OXTRAVPR1AL3MBTL1TDP1 | |
| SCHEMBL4984606 | 0.84 | SMO (0.38) | SMN1; SMN2OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL4984447 | 0.84 | OXTR (0.41) | SMN1; SMN2OXTRAVPR1AL3MBTL1MEN1 | |
| SCHEMBL4987284 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2OXTRAVPR1AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | SMN1; SMN2 3713/4885OXTR 2187/4885AVPR1A 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.