⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789007 | 0.79 | — | — | |
| SCHEMBL8724616 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL8908083 | 0.77 | ALDH1A1 (0.33) | — | |
| SCHEMBL11210735 | 0.74 | — | — | |
| SCHEMBL6141173 | 0.74 | — | — | |
| SCHEMBL2090540 | 0.72 | — | — | |
| SCHEMBL24856 | 0.71 | — | — | |
| SCHEMBL634253 | 0.71 | — | — | |
| Isopropyl Alcohol SCHEMBL7592214 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL12353675 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754607-B | Oxadiazole compound and application thereof | 沈阳化工大学 | 2023-09-05 | — | — | CN | claimed |
| CN-113754607-A | Oxadiazole compound and application thereof | 沈阳化工大学 | 2021-12-07 | — | — | CN | claimed |
| CN-106831638-A | 5 substituted thiazole amides compounds and preparation method and application | 中国农业大学 | 2017-06-13 | — | — | CN | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| EP-0000931-B1 | ENZYMATIC CLEAVAGE OF N-ACYL-THIENAMYCINS | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | claimed |
| US-4162193-A | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO., INC. (US) | 1979-07-24 | — | — | US | claimed |
| EP-0000931-A1 | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO. INC. (US) | 1979-03-07 | — | — | EP | claimed |
| CN-113754607-B | Oxadiazole compound and application thereof | 沈阳化工大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-113754607-A | Oxadiazole compound and application thereof | 沈阳化工大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-106831638-B | 5-substituted thiazole amide compounds and preparation method and application thereof | 中国农业大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-106831638-A | 5 substituted thiazole amides compounds and preparation method and application | 中国农业大学 | 2017-06-13 | — | — | CN | disclosed |
| US-20080114020-A1 | such as 7,7-Difluoro-2,3-dimethyl-8-hydroxy-9-phenyl-7H-8,9-dihydro-pyrano(2,3-c]imidazo[1,2-a]pyridine; inhibit gastric acid secretion by blockade of the H+/K+-ATPase; reversible proton pump inhibitors (rPPI's) or acid pump antagonists (APA's) bind reversibly to H+/K+-ATPase; gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-4196291-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4162193-A | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO., INC. (US) | 1979-07-24 | — | — | US | disclosed |
| EP-0000931-A1 | Enzymatic cleavage of N-acyl-thienamycins | MERCK & CO. INC. (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4141978-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | disclosed |