Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 13/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991713 | 0.90 | AOC3 (0.34) | AOC3 | |
| SCHEMBL4987507 | 0.87 | AOC3 (0.41) | AOC3POLBKMT2A | |
| SCHEMBL4988776 | 0.86 | AOC3 (0.35) | AOC3 | |
| SCHEMBL4988488 | 0.86 | AOC3 (0.32) | AOC3 | |
| SCHEMBL4986328 | 0.86 | OGA (0.34) | AOC3POLBKMT2A | |
| SCHEMBL4991741 | 0.83 | AOC3 (0.45) | AOC3MAPTPOLBKMT2A | |
| SCHEMBL4986002 | 0.83 | AOC3 (0.36) | AOC3MAPTGAAPOLBKMT2A | |
| SCHEMBL4871391 | 0.82 | AOC3 (0.39) | AOC3 | |
| SCHEMBL4877774 | 0.82 | NPC1 (0.38) | AOC3POLB | |
| SCHEMBL4987280 | 0.82 | AOC3 (0.37) | AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119462-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119462-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | VCAM1, ICAM1, VAPB | AOC3 202/4885MAPT 430/4885GAA 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.