Carbamic Acid

Carbamic Acid

SCHEMBL4986286

CC(=O)Nc1nc(CCc2ccc(NC=NC(=O)O)cc2)c(C(=O)NCCNC(=O)Cc2ccccc2)s1.NC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 14/20 0.45
SCD O00767 1/20 0.40
POLB P06746 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 2/20 0.36
CSNK1D P48730 1/20 0.36
GLS O94925 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL5670031 0.91 AOC3 (0.43) AOC3
Carbamic Acid SCHEMBL4992521 0.90 AOC3 (0.48) AOC3SCDPOLBRAB9AMEN1
Carbamic Acid SCHEMBL4876510 0.89 AOC3 (0.44) AOC3SCDPOLBRAB9AMEN1
Carbamic Acid SCHEMBL4873556 0.87 AOC3 (0.48) AOC3RAB9AMEN1NPC1KMT2A
Carbamic Acid SCHEMBL4984088 0.87 AOC3 (0.42) AOC3
Carbamic Acid SCHEMBL4985437 0.86 AOC3 (0.42) AOC3POLBRAB9AMEN1NPC1
Carbamic Acid SCHEMBL4866963 0.86 AOC3 (0.43) AOC3
Carbamic Acid SCHEMBL4990503 0.86 AOC3 (0.41) AOC3
SCHEMBL14019588 0.85 AOC3 (0.47) AOC3SCDPOLBRAB9AMEN1
Carbamic Acid SCHEMBL5670973 0.85 AOC3 (0.47) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608365-B1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE R TECH UENO LTD (JP) 2013-10-02 EP disclosed
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE SUCAMPO AG (CH) 2008-05-22 US disclosed
US-7125901-B2 Thiazole derivatives ASTELLAS PHARMA INC. (JP) 2006-10-24 US disclosed
US-20060128770-A1 Thiazole derivatives FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE VCAM1, ICAM1, VAPB AOC3 202/4885SCD 715/4885POLB 3010/4885
US-20060128770-A1 Thiazole derivatives VCAM1, ICAM1, TXNL1 AOC3 782/4885SCD 2681/4885POLB 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.