Squalane

Squalane

SCHEMBL4987345

CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C.OCCO

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.78
BLM P54132 1/20 0.54
PTPN1 P18031 3/20 0.52
ALOX15 P16050 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 1/20 0.47
ACE2 Q9BYF1 1/20 0.35
PTPN2 P17706 1/20 0.35
CDC25B P30305 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GBA1 P04062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28228861 0.92 LMNA (0.74) LMNABLMPTPN1ALOX15MEN1
SCHEMBL3568842 0.92 LMNA (0.74) LMNABLMPTPN1ALOX15MEN1
SCHEMBL3575766 0.92 LMNA (0.74) LMNABLMPTPN1ALOX15MEN1
Squalane SCHEMBL28103427 0.90 LMNA (0.70) LMNABLMPTPN1ALOX15MEN1
SCHEMBL16167217 0.90 LMNA (0.70) LMNABLMPTPN1ALOX15MEN1
SCHEMBL4821885 0.90 LMNA (0.70) LMNABLMPTPN1ALOX15MEN1
SCHEMBL12960699 0.90 LMNA (0.70) LMNABLMPTPN1ALOX15MEN1
SCHEMBL9060842 0.90 LMNA (0.70) LMNABLMPTPN1ALOX15MEN1
SCHEMBL27965 0.89 LMNA (0.68) LMNABLMPTPN1ALOX15MEN1
SCHEMBL2351564 0.89 LMNA (0.68) LMNABLMPTPN1ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371740-B2 Phosphorylated glyceryl ether aluminum salt KAO CORPORATION (JP) 2008-05-13 US disclosed
EP-1514872-B1 Phosphorylated glyceryl ether aluminium salts KAO CORP (JP) 2006-11-22 EP disclosed
US-20050234023-A1 Phosphorylated glyceryl ether aluminum salt KAO CORPORATION (JP) 2005-10-20 US disclosed
CN-1626538-A Phosphorylated glyceryl ether aluminium salts KAO CORP (JP) 2005-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050234023-A1 Phosphorylated glyceryl ether aluminum salt PHOSPHO1, PLA2G2C, PPM1A LMNA 3262/4885BLM 3645/4885PTPN1 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.