SCHEMBL4987346

SCHEMBL4987346

CC(C)(C#N)ON1C(C)(C)CCCC1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969177 0.92
SCHEMBL4798083 0.85
SCHEMBL7473328 0.76
SCHEMBL6543844 0.76 GAA (0.36)
SCHEMBL4990536 0.76
SCHEMBL7968306 0.72
SCHEMBL7070460 0.69 SMN1; SMN2 (0.35)
SCHEMBL9075719 0.68 HTT (0.32)
SCHEMBL27869141 0.67
SCHEMBL24663309 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7388052-B2 Process for the preparation of block copolymers POLIMERI EUROPA S.P.A. (IT) 2008-06-17 US disclosed
EP-1519970-B1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA SPA (IT) 2007-10-24 EP disclosed
US-20070219329-A1 polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; POLIMERI EUROPA S.P.A. (IT) 2007-09-20 US disclosed
EP-1519970-A1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS Polimeri Europa S.p.A. (IT) 2005-04-06 EP disclosed
WO-2004005361-A1 PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS POLIMERI EUROPA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1375476-A1 A new process for the synthesis of alkoxyamines active in controlled radical polymerization Bayer Aktiengesellschaft (DE) 2004-01-02 EP disclosed
US-20040002606-A1 Process for the synthesis for alkoxy amines and their use in controlled radical polymerization BAYER AKTIENGESELLSCHAFT (DE) 2004-01-01 US disclosed
US-6258905-B1 Stabilized, unimolecular initiators for hydrocarbon polymerization WU ZHE (US) 2001-07-10 US disclosed
EP-0135280-B1 NEW POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREBY COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1993-05-12 EP disclosed
US-4581429-A Polymerization process and polymers produced thereby COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1986-04-08 US disclosed
EP-0135280-A2 New polymerization process and polymers produced thereby COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1985-03-27 EP disclosed