⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987346 | 0.76 | — | — | |
| SCHEMBL24663309 | 0.74 | — | — | |
| SCHEMBL13567071 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL1305578 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL13008584 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL4982858 | 0.71 | MAPK1 (0.44) | — | |
| SCHEMBL4747481 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL7473648 | 0.70 | GAA (0.31) | — | |
| SCHEMBL15698088 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL20712947 | 0.69 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125122-A1 | PROCESS FOR THE PRODUCTION OF A (CO)POLYMER COMPOSITION BY MEDIATED FREE RADICAL CHAIN GROWTH POLYMERIZATION | DOW GLOBAL TECHNOLOGIES INC. | 2010-05-20 | — | — | US | disclosed |
| US-7592392-B2 | Synthesis of functional polymers for use in organic synthesis and combinatorial chemistry | MERCK & CO. INC. (US) | 2009-09-22 | — | — | US | disclosed |
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |