⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461401 | 0.77 | — | — | |
| SCHEMBL321630 | 0.77 | GABRA1 (0.36) | — | |
| SCHEMBL17791711 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL2034501 | 0.76 | — | — | |
| SCHEMBL319317 | 0.76 | HTT (0.31) | — | |
| SCHEMBL2744357 | 0.74 | — | — | |
| SCHEMBL609349 | 0.74 | — | — | |
| SCHEMBL607809 | 0.74 | CHRM1 (0.38) | — | |
| SCHEMBL38660261 | 0.72 | GRIK1 (0.32) | — | |
| SCHEMBL2744347 | 0.72 | POLB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125473-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-29 | — | — | US | disclosed |
| US-20080119536-A1 | SUBSTITUTED IMIDAZOLES | PFIZER LIMITED (GB) | 2008-05-22 | — | — | US | disclosed |
| US-20070167506-A1 | SUBSTITUTED IMIDAZOLES | PFIZER INC. (US) | 2007-07-19 | — | — | US | disclosed |