Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 7/20 | 0.47 |
| ▸ | F13A1 | P00488 | 6/20 | 0.47 |
| ▸ | TGM1 | P22735 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387495 | 0.89 | KDM4E (0.51) | KDM4ELMNAPOLBHSD17B10F10 | |
| SCHEMBL4386052 | 0.88 | POLB (0.52) | KDM4ELMNAPOLBHSD17B10F10 | |
| SCHEMBL4388871 | 0.86 | NPSR1 (0.56) | KDM4ELMNAMMP2MMP9POLB | |
| SCHEMBL4393341 | 0.81 | POLB (0.52) | KDM4ELMNAPOLBNPSR1ALDH1A1 | |
| SCHEMBL8290690 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1 | |
| SCHEMBL15743850 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1 | |
| SCHEMBL9377286 | 0.78 | SMN1; SMN2 (0.47) | NPSR1ALDH1A1 | |
| SCHEMBL29816738 | 0.78 | KMT2A (0.49) | NPSR1 | |
| SCHEMBL20886535 | 0.78 | KMT2A (0.49) | NPSR1 | |
| SCHEMBL19313922 | 0.78 | KMT2A (0.49) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |