Carbamic Acid

Carbamic Acid

SCHEMBL4989598

CC(=O)Nc1nc(CCc2ccc(NC=NC(=O)O)cc2)c(C(=O)N[C@H](C(=O)N(C)C)[C@H](C)O)s1.NC(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 20/20 0.41
MAOB P27338 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL4875379 0.92 AOC3 (0.43) AOC3MAOB
Carbamic Acid SCHEMBL4871993 0.89 AOC3 (0.40) AOC3MAOB
Carbamic Acid SCHEMBL4982527 0.87 AOC3 (0.39) AOC3MAOB
Carbamic Acid SCHEMBL4876992 0.87 AOC3 (0.43) AOC3MAOB
SCHEMBL14019601 0.85 AOC3 (0.43) AOC3MAOB
Carbamic Acid SCHEMBL4988362 0.85 AOC3 (0.44) AOC3MAOB
Hydrochloric Acid SCHEMBL4871368 0.84 AOC3 (0.43) AOC3MAOB
Carbamic Acid SCHEMBL5670973 0.84 AOC3 (0.47) AOC3MAOB
Carbamic Acid SCHEMBL4875938 0.83 AOC3 (0.41) AOC3MAOB
SCHEMBL4989591 0.83 AOC3 (0.37) AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608365-B1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE R TECH UENO LTD (JP) 2013-10-02 EP disclosed
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE SUCAMPO AG (CH) 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119462-A1 METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE VCAM1, ICAM1, VAPB AOC3 202/4885MAOB 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.