Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402455 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7855506 | 0.88 | SMN1; SMN2 (0.74) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL2406326 | 0.83 | KDM4E (0.69) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4987528 | 0.81 | SMN1; SMN2 (0.76) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL9449541 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| Tryptophan SCHEMBL5309760 | 0.80 | KDM4E (0.76) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4628875 | 0.80 | KDM4E (0.77) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL13762546 | 0.80 | KDM4E (0.77) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL14458882 | 0.80 | KDM4E (0.77) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL891879 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103555782-B | Production of monatin and monatin precursors | 嘉吉有限公司 | 2017-04-12 | — | — | CN | disclosed |
| US-8669080-B2 | Mutated D-aminotransferase and method for producing optically active glutamic acid derivatives using the same | AJINOMOTO CO., INC. (JP) | 2014-03-11 | — | — | US | disclosed |
| US-8435765-B2 | Polypeptides and biosynthetic pathways for the production of monatin and its precursors | CARGILL, INCORPORATED (US) | 2013-05-07 | — | — | US | disclosed |
| US-20080193975-A1 | MUTATED D-AMINOTRANSFERASE AND METHOD FOR PRODUCING OPTICALLY ACTIVE GLUTAMIC ACID DERIVATIVES USING THE SAME | AJINOMOTO CO., INC. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-7351569-B2 | Aldolase and production process of substituted α-keto acids | AJINOMOTO CO., INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20050153405-A1 | Novel aldolase and production process of substituted alpha-keto acids | AJINOMOTO CO., INC. (JP) | 2005-07-14 | — | — | US | disclosed |