Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629672 | 0.87 | GRM5 (1.00) | GRM5 | |
| SCHEMBL2172448 | 0.83 | GRM5 (0.80) | GRM5 | |
| SCHEMBL4630084 | 0.75 | GRM5 (1.00) | GRM5 | |
| SCHEMBL568039 | 0.73 | JAK2 (0.38) | GRM5PTGS2 | |
| SCHEMBL4630177 | 0.73 | GRM5 (1.00) | GRM5 | |
| SCHEMBL1023486 | 0.73 | GRM5 (0.64) | GRM5 | |
| SCHEMBL1020980 | 0.73 | GRM5 (0.67) | GRM5 | |
| SCHEMBL4630041 | 0.71 | GRM5 (0.75) | GRM5 | |
| SCHEMBL1023214 | 0.70 | GRM5 (0.60) | GRM5 | |
| SCHEMBL1022403 | 0.70 | GRM5 (0.60) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606277-B8 | IMIDAZOL-4-YL-ETHYNYL-PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-10-15 | — | — | EP | claimed |
| EP-1606277-A1 | IMIDAZOL-4-YL-ETHYNYL-PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-21 | — | — | EP | claimed |
| WO-2004080998-A1 | IMIDAZOL-4-YL-ETHYNYL-PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-23 | — | — | WO | claimed |